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Understanding Addiction

Learn how the effects of addiction on brain chemistry are profound, altering not only how individuals interact with their addictive focus but also impacting other facets of their lives.

What Is Addiction?

Addiction is a condition characterised by an uncontrollable engagement with a substance or activity, despite its potential harm to the individual or those around them. The term, rooted in Latin, translates to “enslaved by.” The essence of addiction lies not in the substance or activity itself, but in its overwhelming impact on a person’s life and their perceived inability to reign in this control.

The effects of addiction on brain chemistry are profound, altering not only how individuals interact with their addictive focus but also impacting other facets of their lives. Addiction manifests in three primary ways:

  • An intense craving for the object of addiction
  • A loss of control in managing its use
  • Persistent involvement with it, despite clear
    physical or psychological damage

Common forms of addiction in today’s society include smoking, gambling, illicit drug use, prescription medication misuse, sexual addiction, and, increasingly, technology addiction. Some addictions intertwine with everyday activities. However, in these cases, the manner of engagement is often reckless or harmful, accompanied by a sense of compulsion and lack of control, as seen in shopping addictions or compulsive eating disorders.

Addictions can profoundly influence all areas of your life. The challenges of substance misuse are not limited to the detrimental effects on the body and mind. Additionally, the intrinsic nature of addiction often leads individuals to distance themselves from family and friends, coupled with potential hardships in their professional life. These factors contribute to heightened feelings of isolation and daily life difficulties, which in turn can intensify the reliance on addictive behaviours as a means for escape and handling perceived stressful situations.

Young group of people enjoying a party taking drugs and drinking alcohol

What are the Causes of Addiction?

Engaging in certain behaviours doesn’t always start with the expectation of developing an addiction. These behaviours might manifest in social contexts, such as initial experiments with alcohol, cigarettes, or illicit substances. On the other hand, some individuals might pursue these behaviours as a perceived solution to a problem, like gambling driven by financial distress. 

Addiction is acknowledged as a chronic disease that modifies the brain’s structure and function. While genetic vulnerability plays a role in the risk of developing an addiction, it’s not a definitive factor. To comprehend the cause of addiction, it’s crucial to explore the concept of the ‘pleasure principle’.

The Pleasure Principle

All pleasurable activities are experienced in the brain the same way, through a release of the neurotransmitter dopamine in a particular region of the brain known as the nucleus accumbens. This is referred to as the ‘reward centre’ of the brain. The likelihood that a particular activity or substance will lead to addiction is directly related to the speed and amount of dopamine that is released in response to it.

Addictive substances such as cocaine, amphetamines, and “legal highs”, etc., function by artificially flooding this part of the brain with dopamine. Inhaling or injecting a drug results in a faster release of dopamine than ingesting a tablet, making the former methods more addictive to the brain.

The reward circuit of the brain is intimately linked with how learning and memory are formed as well (via another related neurotransmitter such as glutamate). It is believed that the simultaneous surge of dopamine and glutamate during intensely pleasurable activities forges a strong association between the behaviour and the sensation of pleasure. This creates a compelling urge to repeat the behaviour.

Group of young people out enjoying the night club scene drinking alcohol and partying

Addictive drugs and behaviours can induce a release of dopamine that is up to 10 times more potent than that provided by more natural pleasures in life. The brain cannot manage this, and the dopamine receptors become overwhelmed. In response to being inundated by floods of dopamine, the brain starts to produce less dopamine in response to the stimulus and in general. It may also reduce the number of dopamine receptors available to ‘receive’ the dopamine. 

These are two strategies the brain might use to protect itself from excessive dopamine secretion. The outcome of this is less pleasure from regular activities and less pleasure from the addictive stimulus that caused the overwhelming release of dopamine initially. In effect, the addictive substance feels as though it is no longer ‘working’, as it does not produce the same dopamine high as before. This process is known as tolerance.

Consequently, compulsion becomes dominant. The person no longer derives the same sense of pleasure from the substance or behaviour they were accustomed to. Nevertheless, they continue to crave the pleasure which the brain now associates with that particular substance or activity. The individual’s behaviour may become increasingly reckless as they consume more of the substance, or engage more with the activity that produced the original ‘high’, in a desperate attempt to recapture the feeling they had when they first started. However, this will never be achievable, as the brain has altered its structure to deal with the dopamine differently. As a result, the individual might start experimenting with different substances or behaviours, trying to attain the same level of pleasure as before.

In addition to the tolerance mentioned above, the part of the brain associated with memory and learning, which has also been swamped during the reward circuit, has been absorbing environmental and situational cues that have become strongly connected with the sense of pleasure that the substance or behaviour produced. This means that being in the same environments or even with the same people can trigger extremely intense cravings. This explains why someone who is working on their journey towards sobriety can feel very overwhelmed with cravings when they encounter the same or similar environment to one they associate with their addiction, such as a bar or casino, the sight of drug paraphernalia, or just as simple as the friends with whom they normally engage in the pleasurable behaviours.

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Types of Addiction

Addiction manifests in various forms, fundamentally defined by an individual’s interaction with a substance or activity rather than the nature of the substance or activity itself. Common types of addictions are:

  • Alcohol addiction
  • Behavioural addictions
  • Cannabinoid addiction
  • Nicotine addiction
  • Opioid addiction
  • Psychostimulant addiction
  • Food addiction
  • Gambling addiction
  • Sexual addiction

Each category, with its distinct characteristics, encapsulates the broad spectrum of addictive behaviours, shedding light on the diverse challenges they present.

The Stages of Addiction

The journey towards addiction generally unfolds through several stages, reflecting a deepening engagement with the addictive substance or behaviour. Understanding these stages is crucial in comprehending the progression of addiction.

Man depressed at losing all his money gambling on slot machines

Stage 1: Pattern of usage

Initial use of a substance or engagement in a behaviour can evolve into a regular habit. For example, heroin use might leave ‘track marks’ on the arms, while signs of a shopping or gambling addiction could include financial strain or evident struggles with money management. Each addiction presents its own set of indicative signs, hinting at the development of a habitual pattern.

Stage 2: Recklessness

As the individual’s brain and body adapt to the substance or activity, their engagement often becomes more hazardous. This might manifest as increasingly poor decision-making or the combining of different substances to intensify the high, which significantly elevates the risk of adverse effects. The danger of substance misuse is compounded when multiple substances are used in conjunction.

Stage 3: Tolerance

As the brain repeatedly encounters excessive dopamine levels due to a substance or behaviour, it may adapt by reducing dopamine release or decreasing the number of dopamine receptors. This adaptation leads to tolerance, where the individual no longer experiences the same level of pleasure from the substance or behaviour. This reduction in pleasure can be frustrating, driving the person to seek out even riskier ways to achieve the previous ‘high’. Consequently, enjoyment derived from other activities wanes, and the cravings increasingly dominate the person’s life.

Stage 4: Dependence

If the individual regularly uses substances or engages in addictive behaviours and has developed tolerance, they will start to suffer negative effects in the absence of these substances or behaviours. These ‘withdrawal’ symptoms can be intensely uncomfortable. Unable to endure these symptoms, the individual becomes dependent on the substance or behaviour, feeling compelled to continue to avoid withdrawal.

Stage 5: Substance disorder

At this advanced stage, the individual’s entanglement with the substance or behaviour seriously deteriorates their quality of life. It negatively impacts their work, family, and social life, as well as their health. Despite the harm, they feel unable to break free from this destructive cycle.

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Psychology of Addiction

Psychology delves into the emotional and mental health aspects that underpin specific behaviours. While neurobiology sheds light on the mechanisms of addiction, it doesn’t fully explain why individuals may start using substances or why certain individuals are more prone to addiction than others. To understand these in greater detail, psychology examines the traits and personal characteristics that might render someone more susceptible to addiction.

Research in psychology suggests a strong correlation between qualities like impulsivity and sensation-seeking and the likelihood of developing an addiction. Additionally, individuals with a history of trauma or abuse are often found to be more vulnerable to substance misuse disorders. This vulnerability might stem from using substances as a form of ‘self-medication’ to mitigate painful emotions or unmanageable stress levels.

Furthermore, there’s a well-established link between concurrent addiction problems and mental health issues, often referred to as ‘comorbidity’. This relationship can be cyclical, with each condition exacerbating the other, leading to a downward spiral. In medical settings, this is known as a ‘dual diagnosis’ and necessitates a treatment approach distinct from that used for addiction alone.

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Understanding Addiction and Physical Dependence

Behavioural psychology delves into the two most important contrasting modes of control influencing engagement with addictive substances or activities: stimulus control and cognitive control.

  • Stimulus control of behaviour
    This denotes how the brain links particular stimuli with pleasure. In treatments focusing on stimulus control, understanding the stimuli associated with an individual’s addiction is key. For instance, a certain location might trigger intense cravings. Hence, the strategy involves aiding the individual in devising plans to avoid such locations.
  • Cognitive control of behaviour
    In contrast, this pertains to the mental mechanisms employed to eschew the addictive substance or activity. Studies indicate that cognitive control measures are typically diminished in those suffering with addictions. Cognitive therapy aims to enhance and build upon the necessary cognitive skills essential for managing life with an addiction.
Man lying in bed suffering from depression and insomnia

How Substance Abuse Impacts Your Mood

One of the more challenging aspects of a substance abuse disorder is its profound impact on brain structure and, consequently, mood. As addiction progresses, individuals face mood fluctuations resulting from the substance’s effects – the euphoria and subsequent crash associated with drug use, mood swings and depressive states from alcohol, or paranoia and psychosis from cannabis use.

Then there are the withdrawal symptoms – the physical and psychological effects experienced when not under the influence of the substance. Withdrawal can render a person agitated, aggressive, preoccupied, and visibly unhappy. Moreover, changes in brain structure diminish the pleasure derived from everyday activities, making regular life seem unfulfilling, insignificant, and arduous to engage with.

Signs and symptoms of addiction

The primary indicator of an addiction is the consistent engagement in using a substance or partaking in a behaviour, despite it causing various impairments, whether physiological, psychological, or detrimental in other aspects of life. Typically, for an addiction to be diagnosed, at least two of the following symptoms should be present alongside the main symptom of recurrent usage:

  • Individuals find themselves using the substance in larger amounts or over a more extended period than they initially planned.
  • Despite their wishes to reduce or cease their engagement with the substance or behaviour, they feel incapable of doing so.
  • Significant chunks of time are devoted to obtaining, using, or recovering from the effects of the substance.
  • The individual struggles with intense desires or urges to use the substance or engage in the behaviour.
  • The person’s regular obligations at home, work, or school are negatively impacted by their use of the substance or engagement in the behaviour.
  • Continuation of the substance use or behaviour occurs even when it leads to problems.
  • Previously important social, work, or recreational activities are abandoned or reduced.
  • The individual engages in the substance use or behaviour in situations where it poses a risk.
  • Awareness of physical or psychological issues caused or worsened by the substance or behaviour does not deter its use.
  • More of the substance is required to achieve the same effect, or the current amount does not produce the same effect as before.
  • Physical or psychological adverse effects are experienced when the substance use or behaviour is reduced or stopped.

The severity of an addiction is generally classified by the number of these symptoms present. A mild condition is typically indicated by two to three symptoms, a moderate addiction disorder is suggested by four to five symptoms, and the presence of six or more symptoms is indicative of a severe addiction, and in this case professional help should be sought.

Woman crying during therapy session as psychologist delivers news about her addiction

Diagnosis of Addiction

Securing a diagnosis of addiction is a task strictly for a mental health professional. This isn’t a decision one should make independently, whether it’s about oneself or a loved one. The diagnostic process is complex, typically involving a collaboration among GPs, psychologists, and psychiatrists, and it necessitates a comprehensive assessment of the individual’s current difficulties, along with their personal and family history.

It’s imperative for mental health experts to fully evaluate the person to exclude any comorbid diagnoses. ‘Comorbid’ denotes the occurrence of two different issues concurrently, which can render the diagnosis and treatment planning more intricate. For instance, someone might initially present with symptoms of substance misuse. Yet, during an assessment with a psychologist, it could emerge that this misuse is intricately linked with other mental health problems.

Termed as ‘dual diagnosis’, this situation demands a treatment and management strategy that differs from approaches used when substance misuse is the only issue. Hence, it’s vital for the individual to undergo a thorough assessment by a mental health practitioner. Such evaluations ensure a holistic view of the person’s situation, leading to more effective and tailored treatment approaches.

Consequences of Addiction

The repercussions of addiction are profoundly detrimental, affecting one’s emotional and physical health in various ways. Each addiction type poses unique risks, impacting the individual’s health and life quality differently. Drug abuse, for example, poses severe threats to both mental and physical health and can critically disrupt one’s ability to manage their life, affecting crucial elements like employment and family relationships. Sexual addiction, in contrast, carries distinct risks, including the potential for contracting STDs and the possibility of causing emotional harm to loved ones due to impulsive sexual behaviours.

On a different note, gambling addiction introduces significant financial risks, which can have disastrous consequences not only for the individual but also for anyone financially linked to them. A unifying factor in all addictions is their overwhelming control over the affected individual. This control is due to changes in the brain’s structure, causing the addictive substance or behaviour to become the focal point of their existence. Consequently, normal life activities lose their appeal and significance, a result of reduced dopamine levels and receptor activity. The individual then finds joy only in their addictive behaviour or substance, leading to a neglect of previously important aspects of their life.

This shift can have a profound impact on their ability to maintain priorities or a rational perspective. Simple decisions and responsibilities, seemingly obvious to those not battling addiction, such as maintaining a job to support oneself financially, investing in relationships to preserve a marriage, or caring for children, can become neglected in the face of substance dependency.

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Dangers of Multi-Substance Addiction

Multi-substance addiction poses unique challenges due to the compounded risks associated with using multiple substances concurrently. The dangers inherent in any illicit substance are magnified when combined with another. Research indicates that simultaneous use of multiple substances can inflict significant brain damage, adversely affecting memory and the capacity to learn new information.

Co-Occurring Disorders:
Mental Health Issues and Addiction

The term ‘comorbidity’ is used to describe the simultaneous occurrence of two conditions, without necessarily attributing causation. The relationship between mental health issues and substance abuse is complex and intertwined. Substance use can aggravate mental health symptoms, as seen in cases where cannabis use is linked to psychosis, including hallucinations and delusions.

Additionally, it’s common for individuals with mental health disorders to engage in substance use as a means of ‘self-medication’, attempting to alleviate adverse psychological states. This practice can further impair mental health, particularly in those suffering from trauma-related disorders like childhood abuse or post-traumatic stress disorder. There’s every growing evidence suggesting that the origins of addiction and mental health problems may be interconnected, potentially rooted in genetic factors or early life trauma.

Living with and Managing Life with Addiction

The impact of addiction extends far beyond the individual. It significantly affects those close to them. The changes in the brain’s structure and function due to addiction make it a daunting challenge to overcome alone. Seeking guidance from a GP, or advocating for someone you care about, is essential in managing this intricate condition.

Helping Someone with Addiction

Initiating a conversation with someone battling addiction is complex and emotionally laden. Intervention support, offered by various treatment centres, can provide crucial emotional guidance and expertise in these situations. It is also important for those around the addicted individual to seek support. Consulting a GP or referring to the resources at the end of this article could offer valuable assistance for relatives and friends of those struggling with addiction.

Top Risk Factors for Addiction

Addiction is a condition of immense complexity, stemming from various factors. It is impossible to pinpoint a single causative factor. However, there are identifiable risk factors that may increase the likelihood of addiction. These include genetic predispositions, environmental influences, and epigenetic changes.

Genetic factors

Studies indicate that genetics may be responsible for nearly half the risk associated with developing a substance disorder. One significant genetic factor is a gene that affects how brain receptors interact with dopamine, potentially increasing the propensity for addiction-related dopamine highs. Additionally, the manner in which an individual’s body responds to stress can also be a genetic factor, with higher resilience possibly reducing the likelihood of developing a substance disorder.

Environmental factors

A critical aspect in the development of substance misuse disorders lies in the environment surrounding an individual. A notable risk factor is the lack of parental support combined with exposure to family members who themselves struggle with substance misuse. Experiencing abuse, be it emotional, physical, or sexual, significantly escalates the risk of future substance misuse issues.

Peer influence is another key factor. The social circles one is part of, especially those involving substance misuse, can markedly increase the likelihood of developing an addiction. Conversely, factors such as social class, perceived social mobility, and stable employment can serve as protective barriers against substance misuse.

Epigenetic factors

Epigenetics explores how our environment and upbringing can influence the expression of our genes, determining how they manifest in behaviours and outcomes. This field investigates why individuals with identical genes may exhibit different traits. For instance, one might develop an addiction while the other does not. Epigenetic research has garnered significant interest in recent years, particularly concerning its role in enhancing our understanding the complexities of addiction.

One intriguing aspect of epigenetics is its potential hereditary impact, suggesting that epigenetic changes can be passed down to offspring, thereby influencing their behaviours. This underscores the critical role of epigenetic studies in comprehending human behaviour, especially addiction.

Psychologists often rely on twin studies to discern the role of genetics in specific traits or behaviours. Since identical twins share the same DNA but may experience different environmental influences (as in cases where they are separated at birth), such studies can shed light on how the same gene may manifest differently or how environmental factors interact with genetic information. In addiction research, it’s been discovered that substance misuse can alter an individual’s DNA.

For example, research has demonstrated that heavy cocaine use can modify the DNA related to the brain’s reward centre. A notable study by McGill University and Bar Ilan University revealed the potential for epigenetic treatments to reverse changes caused by extensive cocaine use, essentially restoring the brain to its pre-addiction state. This discovery signals a significant shift in our approach to addiction treatment and opens up exciting prospects for future developments.

How to Prevent Addiction

As addiction progresses, the initial pleasure derived from the substance or behaviour diminishes. Despite this, the craving for the associated pleasure persists, leading to increasingly reckless attempts to recreate the initial high. However, this pursuit is futile as the brain’s structural changes alter its response to dopamine. Consequently, individuals may experiment with various substances or behaviours in a desperate attempt to regain the former sense of pleasure.

Preventing addiction involves understanding and mitigating these risk factors. Early education about the dangers of substance misuse, building strong support networks, and promoting healthy coping mechanisms for stress and trauma are essential. Additionally, fostering environments that limit exposure to addictive substances and behaviours, coupled with effective public health policies, can play a crucial role in prevention.

Couple arguing over family finances after husband spent all the money on his addiction

Cost of Addiction to Families and Society

Addiction imposes a heavy toll, both financially and emotionally, on families and society. From a financial standpoint, the cost of sustaining an addiction can be substantial, often leading to the deprioritisation of savings and other financial goals. As the addiction deepens, maintaining employment becomes challenging, further straining financial resources and adding another layer of stress.

Emotionally, addiction can strain family relationships to breaking point. Children in families where addiction is present are more likely to face similar struggles. The broader societal impact is significant too, with addiction draining government resources, contributing to increased crime rates, and exacerbating public health issues, especially related to mental health.

Types of Addiction Treatment

Addiction imposes a heavy toll, both financially and emotionally, on families and society. From a financial standpoint, the cost of sustaining an addiction can be substantial, often leading to the deprioritisation of savings and other financial goals. As the addiction deepens, maintaining employment becomes challenging, further straining financial resources and adding more stress.

Emotionally, addiction can strain family relationships to breaking point. Children in families where addiction is present are more likely to face similar struggles. The broader societal impact is significant too, with addiction draining government resources, contributing to increased crime rates, and exacerbating public health issues, especially related to mental health.

  • Addiction withdrawal and detox

This initial phase is fundamental in the journey to overcome addiction. It offers specialist support to manage the intense cravings experienced during the early stage of ceasing substance use. Detoxification provides medically-assisted care to navigate the complex physical and psychological effects of withdrawal symptoms.

  • Treatment and rehab

Post-detox, the focus shifts from managing the primary physical symptoms of withdrawal to addressing the psychological aspects. This stage is crucial for offering psychological support and imparting vital skills for long-term management of addiction.

  • Medications used in addiction treatment

The treatment may incorporate various medications such as benzodiazepines, antidepressants, and specific drugs for managing opiate withdrawal.

  • Behavioural therapy for addiction

This form of therapy aims to equip individuals with skills to handle cravings, deal with stress and challenging emotions, and reconstruct their lives post-addiction. It is a critical component of a comprehensive treatment plan, addressing the behavioural aspects of addiction.

People meeting a support group for addicts

Addiction Support Groups in the UK

Across the UK, a lot of support groups cater to specific addictions and individual requirements. For those battling addiction, options like Alcoholics Anonymous and Narcotics Anonymous are readily available. Moreover, various groups are also accessible for family members and friends close to someone struggling with addiction. 

Addiction Statistics

Across the UK, a lot of support groups cater to specific addictions and individual requirements. For those battling addiction, options like Alcoholics Anonymous and Narcotics Anonymous are readily available. Moreover, various groups are also accessible for family members and friends close to someone struggling with addiction. 

  • Genetic factors contribute to approximately 40-60% of the risk for an individual becoming addicted to a substance.
  • Research indicates that the age at first alcohol consumption influences addiction risk. Notably, 16% of alcoholics began drinking before the age of 12.
  • The National Bureau of Economic Research highlights a significant link between mental illness and substance abuse. Statistics show:

38% of people with mental health issues struggle with alcohol
44% encounter issues with cocaine
40% face challenges with cigarettes

Frequently asked questions

Addiction is the process of becoming dependent on a substance or activity, characterised by an inability to control cravings or cease its use or engagement.

Effective treatment for addiction typically occurs at specialised rehabilitation centres where comprehensive medical and psychological support is provided. This support is crucial for managing the wide range of symptoms and challenges encountered during withdrawal and for long-term recovery.     

Addiction often starts unsuspectingly when engaging with a substance or activity. It gradually turns into a habit, with increased tolerance and reliance on the substance or activity ensuing over time.

Drug use leads to an excessive release of dopamine, overwhelming the brain’s reward centre. In response, the brain reduces dopamine production or the number of dopamine receptors. This adaptation necessitates increased substance use to achieve the same effect and leads to dependence, characterised by withdrawal symptoms when the substance is not used.

Substance abuse escalates to addiction when the brain adapts by reducing dopamine levels or dopamine receptor availability. This adaptation drives an increased need for the substance, with negative effects experienced during periods of non-use.

The likelihood of developing an addiction is influenced by various factors, including genetics and environmental factors such as challenging or abusive upbringings, poverty, strained family relationships, and social isolation.

Most addiction treatments focus on long-term symptom management. Many individuals successfully learn to manage their addiction, effectively reducing or eliminating cravings and restoring normal function.

Typically, the most severe withdrawal symptoms last for about 48 hours, but they can persist for 1-2 weeks.

FREE Addiction Assessment

If you or a loved one are struggling with addiction, we understand the challenges you’re facing and we’re here to offer compassionate help. 

Our highly trained advisers are available to speak to you right away, simply call 0808 252 3379 today. 

We can discuss your concerns in complete confidence, explore the options for treatment, and help you to understand what will work best for you. 

We’ll also help you to book your free addiction assessment there and then, with appointments usually available within only a few days. 

We understand that taking the first step can be the most difficult, but we’re here to support – with no pressure or judgement. 

Professional and compassionate help is just a phone call or click away.

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